- Actor David Boreanaz is also known for playing the role of vampire superhero Angel on the eponymous WB Network television series Angel.
- Actress Emily Deschanel is also known for playing the role of Pam Asbury on the 2002 Stephen King miniseries Rose Red. She has also appeared in episodes of Law&Order:SVU, Providence and Crossing Jordan.
- Jonathan Adams is a series regular on Bones in season 1 only.
- Eric Millegan is a series regular on Bones from season 1 until midway through season 3.
- Actor Sam Trammell, who plays Ken Thompson in this episode, will go on to play a leading role in the HBO TV series True Blood as shape-shifting bartender Sam Merlotte.
- Actors John M. Jackson and Shawn McDonald are uncredited for their participation in this episode.
"Pilot" is the premiere episode of the crime procedural television series Bones. It was directed by Greg Yaitanes and written by series creator Hart Hanson. It first aired on the FOX Network on September 13th, 2005. The series is inspired by the works of forensic anthropologist Kathy Reichs, who is also the author of a series of novels from which the show is based. Bones stars Emily Deschanel as the brilliant, yet socially inept forensics anthropologist Doctor Temperance Brennan. She is partnered with FBI Special Agent Seeley Booth, played by David Boreanaz, and is based out of the fictional Jeffersonian Institute in Washington, D.C.. Seeley's nickname for Brennan is "Bones", due to her occupational proclivities and he refers to her team of specialists as "Squints". The other cast members on the series includes Brennan's team, which is played by Michaela Conlin, Eric Millegan and TJ Thyne in the respective roles of Angela Montenegro, Zack Addy and Doctor Jack Hodgins. The team's supervisor is Doctor Daniel Goodman played by Jonathan Adams.
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Interesting huh?